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Ultimately, autophagosome-lysosome fusion generates autolysosomes, enabling programmed mitochondrial degradation (Turco et al., 2021)

It is technically difficult to take plasma samples for the MDA level tests at such short periods of time therefore the work must be repeated in order to measure the oxidative stress markers protein carbonyls, whose half-life is much longer thus offering the possibility to identify changes in their levels at different points in time

Although the anxiety and depression symptom instruments that were used have been validated, they are self-report questionnaires and only evaluated symptom severity, and they do not necessarily have diagnostic value

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