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The incidence of SJS is estimated to be between 1.1 and 7.1 cases per million person-years.1 SJS is currently considered to be a part of bullous disease syndromes [SJS, SJS- toxic epidermal necrolysis (TEN) overlap syndrome, and TEN] in which keratinocyte cell death results in subepidermal separation

The sophisticated regulation of cell wall components also contributes to its pathogenicity

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