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Research has also investigated DRP-104 for its broader implications in tumor biology, including potential effects on oxidative stress balance, growth signaling pathways such as mTOR, and tumor microenvironment nutrient competition

Lobeline has not been investigated in GBM but has been shown to reverse drug resistance in cancer cells and to decrease colon cancer growth [21, 22]

The safety and efficacy of supplements can vary, and determining the correct dosage is essential to avoid possible side effects

But an assortment of unapproved peptides ranging from injectables, creams, capsules, and nasal sprays are trending in an unregulated marketplace after the Biden administration in 2023 prohibited them from being manufactured, finding safety risks and lack of human studies to support their use