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They contain different mixtures of aromaimpact compounds, such as caffeine, CGA, trigonelline, melanoidins, and diterpenes that significantly determine the perceived quality of coffee

Theriogenology 74 , 968978 (2010)

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Time of day significantly impacts oxidation-reduction reactions in the brain [51,52,53], which may influence the efficacy of antioxidant therapeutics in the treatment of neurologic and psychiatric conditions