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CISH Polyclonal Antibody-BS65401 Size:50µl Specificity: Phospho-RUNX1/RUNX3 (Ser435/Ser397) Antibody detects

SKU: 78823254303

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Description

Specificity: Phospho-RUNX1/RUNX3 (Ser435/Ser397) Antibody detects endogenous levels of RUNX1/RUNX3 only when phosphorylated at Ser435/397

It is active in the reduced glutathione conjugation and also displays glutathione peroxidase activity with cumene hydroperoxide

Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SCP3

CISH Polyclonal Antibody-BS65401 Size:50µl Specificity: Phospho-RUNX1/RUNX3 (Ser435/Ser397) Antibody detectsCISH Polyclonal Antibody Product: Rabbit IgG, 1mg ml in PBS with 0. 02% sodium azide, 50% glycerol, pH7. 2 Catalogue Numbers: BS65401 50, BS65401 100 Sizes: 50l, 100l Swiss Prot: Q9NSE2 Host: Rabbit Reactivity: Rat, Mouse Applications: WB, IHC Background: The suppressor of cytokine signaling (SOCS) family members are negative regulators of cytokine signal transduction that inhibit the Jak Stat pathway. The SOCS family consists of at least 8 members

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