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Association between abnormal maternal serum levels of vitamin B12 and preeclampsia: a systematic review and meta-analysis. Nutrition Reviews 79.5 (2021): 518-528

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Functional assays confirmed P3s critical role: the P3A mutant failed to promote HUVEC proliferation in CCK-8 assays

Although several laboratory and animal studies suggest potential regenerative effects, there are scant high-quality randomized controlled human trials demonstrating its safety or efficacy