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A recent metabolomics study found that male NSW exhibited higher glycoprotein acetyls (GlycA), which is a marker of chronic low-grade inflammation, along with elevated triglycerides and fatty acids, indicating a potential sex-specific link between NSW, systemic inflammation, and metabolic deregulation 153

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Lidocaine demonstrated a longer duration of effective anesthesia compared to diphenhydramine (81 minutes versus 42 minutes, P = 0.028)