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Emerging evidence also points to specific lncRNAs (e.g., LINC-PINT, NEAT1) that are differentially expressed in HT and may regulate immune-related gene networks (Abdalrahman et al., 2025)

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This approach often neglects the socio-spatial preconditions and implications of going circular. Growing criticism of the urban CE agenda highlights these shortcomings (Dbrowski et al., 2024), noting that circular actions and strategies are not always sustainable (Taelman et al., 2020), can perpetuate the growth-based paradigm and spatial inequalities (Savini, 2024), and fail to fully exploit circularitys potential to drive socially inclusive (Vanhuyse et al., 2022) and regenerative (Williams, 2023) transformations of cities and their hinterlands