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In laboratory studies, BPC-157 has been observed to interact with several biological signaling systems involved in tissue maintenance and repair

Kansanen E, Bonacci G, Schopfer FJ, Kuosmanen SM, Tong KI, Leinonen H, et al

The reduction in absorbance at 560 nm in the presence of antioxidants indicates the neutralization of superoxide anions in the reaction mixture (Bursal and Glin 2011)

HMGB1 translocation from nucleus to the cytoplasm of renal tubular cells induces ferroptosis by binding ACSL4 after renal I/R injury, and inhibition the nuclear cytoplasmic translocation of HMGB1 could inhibit ferroptosis and renal I/R injury