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Many breakfast cereals, soy products, and yeasts are fortified with B12

This means B12 deficiency is real and underdiagnosed, but it is not universal and not everyone experiencing fatigue has a B12 problem

*Correspondence: Julien Baruteau, [email protected] This article was submitted to Drug Metabolism and Transport, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Based on how lipotropic injection regimens are generally used in integrative medicine, B12-related energy benefits may be among the earliest noticeable effects for individuals with suboptimal B12 status