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Other entero-pancreatic hormones and combination of entero-pancreatic hormones in the management of obesity Numerous entero-pancreatic hormones [GIP, glucagon, amylin and peptide YY (PYY) agonists and GIP antagonists] with diverse metabolic actions are currently under investigation either alone or in combination with GLP-1 RA (Fig

Furthermore, it ameliorates hypertrophic cardiomyopathy and reverses diabetes-induced mitochondrial damage by restoring the expression and function of crucial cardiac energy metabolic proteins [37, 228]

The infusion window is brief, which is why simultaneous serum delivery matters more than post-application