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Hepatology 65 , 15571565 (2017)

10.1016/j.intimp.2022.108890 Int

213,485 The nearly 30 high resolution crystal structures of NikRs in various allosteric states reveal four symmetry-related conserved square planar His 3 Cys Ni II coordination complexes per tetramer that promotes a conformational change to a closed conformation competent for DNA binding (Figure 16B