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Statistical analysis The MS data were analyzed using MaxQuant software (version 1.3.0.5.) (Max Planck Institute of Biochemistry, Germany) against the UniprotKB 61 human database (163652 total entries, downloaded 27/05/15)

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This dual anti-inflammatory and pro-survival signaling complements the gene-level anti-inflammatory effects of GHK-Cu and the vascular protection afforded by BPC-157's nitric oxide production, creating coordinated suppression of destructive inflammation while preserving protective immune responses essential for optimal tissue repair