glutathione s-transferase pi transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases Glutathione S-Transferase pi 1/GSTP1 Antibody

Interestingly, SeCyS is efficiently methylated by certain plants, such as Brassica oleracea capitata (kale), Brassica juncea , and Allium tricoccum , which can accumulate high concentrations of Se in the form of selenomethionine (SeMet), resulting in increased levels of methylated metabolites [17, 18]

Furthermore, by securing their metabolic resilience against ferroptosis, DJ-1-competent astrocytes can better provide trophic support, regulate extracellular glutamate, and mitigate neuroinflammatory cascades, all processes that indirectly influence neuronal susceptibility to ferroptotic death (Cao et al., 2020)

10.1002/(sici)1096-8628(19981116)80:3 3.0.co;2-8 39 FuentesJ

doi: 10.1016/j.cbi.2015.11.002 35 KowalewskiM.FinaD.SomkaA.RaffaG