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These medications, which include semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound), act like the bodys own GLP-1 hormone, but in doses much larger than the body produces, to regulate insulin and blood sugar, decrease appetite, and slow down stomach emptying

In comparison, patients who used retatrutide (8 mg and 12 mg once weekly) lost 17.5% at 24 weeks and 24.2% of their body weight after 48 weeks in phase 2 clinical trials

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