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In some embodiments, formulations or compositions described herein comprise therapeutic agent particles wherein the therapeutic agent is a free base, or a salt, or a prodrug of a therapeutic agent, or any combination thereof

The cysteine in whey protein is largely present as glutamylcystine, which is resistant to digestive degradation and serves as an efficient substrate for glutathione synthesis [22]

For a 80 kg person, this translates to 80 to 800 mcg per day

An immediate and then sustained effect on pressure in lower esophageal sphincter, and a postponed effect on pyloric sphincter after either 0.5 mg/kg or 1.0 mg/kg intraperitoneal challenge (white bars), pyloric sphincter seems to be less affected