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References used for calculations and assessment Ahmad, M., Manjantratat, T., Rattanawongsa, W., Muensri, P., Saenmuangchin, R., Klamchuen, A., Aueviriyavit, S., Sukrak, K., Kangwangsupamonkon, W

Open systems, due to the contact of the e-liquid with the metallic components of the device, particularly the heating resistors, can release heavy metals such as iron (Fe), arsenic (As), and nickel (Ni)

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Summary Keywords adolescents, e-cigarettes, nicotine addiction, prevention strategies, public health, vaping Citation Fainardi V, Barbetta E, Petz M, Rizzo L, Ruberti F and Esposito S (2026) The new nicotine epidemic: understanding the systemic harms of e-cigarettes in the adolescent population