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The following may be useful: Soap-free cleaners (soap can exacerbate dryness) Rub with a pumice stone or exfoliating sponge in the shower or bath Moisturizing cream containing urea, salicylic acid or alpha hydroxy acids Current retinoids, Pulse Dye To be Treatment or Intense Pulsed Light (IPL): This can reduce redness (at least temporarily), but not roughness Laser assisted hair removal

So I think there's some relation there between mast cell degranulation and these headaches in hypermobile patients

But I know at least 3 dog owners who are giving BPC to their injured and/or aging dogs