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39,40 Iron overload diseases encompass a wide variety of genetic and acquired conditions

Supporting may be a dramatic decrease of glutathione levels in the rat brain after a paracetamol oral overdose (3.0 g/kg) (4) and brain tissue susceptibility to oxidative stress (high content of peroxidizable unsaturated fatty acids, high oxygen consumption per unit weight, but poorly developed antioxidative defense mechanisms) (5)

May M, Leaver CJ (1994) Arabidopsis thaliana c-glutamylcysteine synthetase is structurally unrelated to mammalian, yeast and E

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