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SKU: 15787837316

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3.1.5 Mechanisms of ferroptosis in myocardial ischemia-reperfusion injury In pathological conditions such as myocardial ischemia-reperfusion injury, the Nrf2/Keap1 pathway becomes dysregulated, leading to the dissociation of Nrf2 from Keap1 and its subsequent translocation into the nucleus

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10.1111/head.13358 Headache 64 VosT.LimS

This leads to cellular iron overload and induces ferroptosis ( 2+ can be released from heme through the activation of heme oxygenase-1 (HO-1), thereby accelerating ferroptosis ( vs