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Some symptoms of a vitamin B12 deficiency include: difficulty thinking brain fog fatigue pale skin weight loss dementia numbness and tingling in hands and feet mood changes decreased appetite constipation A lack of animal protein and following a plant-based diet sans appropriate supplementation can lead to a vitamin B12 deficiency

The medication should be injected subcutaneously into the abdomen, thigh, or upper arm, with rotation of injection sites to prevent lipodystrophy or persistent local reactions

In the acute COVID-19 context, previous studies have demonstrated that vitamin B12 increases the flow of the sulfur amino acid pathway, favoring production of glutathione, an important antioxidant agent, in leukocytes of patients with moderate and severe COVID-19 18

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