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In those cases, the daily intake of B12 isnt able to keep up with the B12 the body is using

Although the reactions catalysed by Gdh2 and Gdh3 are reversible, the Gdh2-catalysed reaction favours the deamination of glutamateits catabolism to -ketoglutarate and ammonium 12

How often you can have vitamin B12 injections is not a fixed number, it depends on why you are deficient, how well you hold on to B12, and the dose you are given

FIGURE 3 2.3 Cartilage Cartilage in healthy joints maintains a precise balance between synthesis and degradation of ECM components, primarily type II collagen and aggrecan, orchestrated by chondrocytes