It activates the Nrf2 pathway and upregulates detoxification enzymes, such as glutathione S-transferase
Yuan R, Tsaih S, Petkova SB, Marin de Evsikova C, Xing S, Marion MA, Bogue MA, Mills KD, Peters LL, Bult CJ, Rosen CJ, Sundberg JP, Harrison DE, Churchill GA, Paigen B (2009) Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels
(PubMed) Tarantini G, Scrutinio D, Bruzzi P, Boni L, Rizzon P, Iliceto S
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