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After Pycnogenol supplementation, the all-adult patients could exhale 70% of their lung volume as compared to 59% at trial start and 63% in response to placebo

* Correspondence: Chunling Pan, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

O 2 - radicals are not highly reactive or toxic, but they are rapidly converted to hydrogen peroxide (H 2 O 2 )

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