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Funct Foods Health Dis 12:198207 Otvos L Jr (2008) Peptide-based drug design: here and now

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Potency is not guaranteed after expiration and taking expired medications can have serious health consequences that may include reduced or no effectiveness, as well as potentially dangerous interactions with other medicines you are taking

An immediate and then sustained effect on pressure in lower esophageal sphincter, and a postponed effect on pyloric sphincter after either 0.5 mg/kg or 1.0 mg/kg intraperitoneal challenge (white bars), pyloric sphincter seems to be less affected