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Self-reactive IgE exacerbates interferon responses associated with autoimmunity

Mitochondrial-derived reactive oxygen species and oxidized mtDNA are potent activators of the NLRP3 inflammasome, driving maturation of IL-1 and IL-18, which in turn enhance Th1 and Th17 responses essential for protection against Candida albicans and Aspergillus fumigatus (Hise et al., 2009

Avoid mixing with incompatible ingredients: GHK-Cu works well with hydrating and antioxidant ingredients but may be less stable when combined with high concentrations of vitamin C or niacinamide

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