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Abstract Background Electronic-cigarette (e-cigarette) use is linked to serious cardiovascular and pulmonary complications, raising public health concerns worldwide, particularly among younger populations

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These brands will likely be grandfathered in (meaning they will not require a substantial equivalence or premarket tobacco application to stay on the market) and also will be able to serve as predicate products for any future products Xcaliber might launch

It is safer than smoking but still not safe