anti-NLRP3/NALP3, mAb (Cryo-2) Protein A/G Magnetic Beads a key intermediate in peptidoglycan

a key intermediate in peptidoglycan biosynthesis

TNF-α and IL-6 production with IC50s of 1

leukocytes

Figure 2: Immunohistochemical staining of endogenous mouse Caspase-1 in mouse spleen using anti-Caspase-1 (p20) (mouse)

anti-NLRP3/NALP3, mAb (Cryo-2) Protein A/G Magnetic Beads a key intermediate in peptidoglycanThe inflammasome is a multiprotein complex that mediates the activation of caspase 1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL) 1? and IL 18. Members of the Nod like receptor family, including NLRP3 NALP3, are critical components of the inflammasome that link danger signals to caspase 1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle