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The most common conditions among those closing are cancer, opioid use disorder, chronic pain, breast cancer, sleep, type 2 diabetes, schizophrenia, gastric cancer, stroke, and colorectal cancer

The latter results have encouraged the clinical evaluation of HGF (VM-202) gene transfer in human trials for neuropathic diabetic pain (NCT01475786) with the encouraging outcome of a 3-month pain relief period (Kessler et al., 2015)

Studies of a mouse model of familial ALS that express human mutant superoxide dismutase 1 (SOD1 G93A ) support a primary role of astrocytes

In some embodiments, the pharmaceutical formulations or compositions described herein are used in combination with (e.g., implantation, short-term use, long-term use, or removal of) implants (e.g., cochlear implants)