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While ROS play a role in cellular signaling and homeostasis at low levels, excess ROS production and/or insufficient antioxidant scavenging leads to oxidative stress (Oswald et al., 2018

doi: 10.3389/fvets.2023.1093274 Received 08 November 2022 Accepted 20 January 2023 Published 16 February 2023 Volume 10 - 2023 Edited by Ayman Abdel-Aziz Swelum, Zagazig University, Egypt Reviewed by Amany Abdel-Rahman Mohamed, Zagazig University, Egypt

It is well documented that cats and dogs with chronic enteropathies (CE), intestinal lymphoma, or exocrine pancreatic insufficiency are often cobalamin (B12) deficient (1,2)

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