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FDA oversight favoring established players, while the Asia Pacific region has seen a more lenient environmentthough this is changing

The UK has comprehensive tobacco control legislation, and tobacco education is embedded in the school curriculum (UK Government Office for Health Improvement and Disparities, 2021

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John Britton, director of the UK Centre for Tobacco and Alcohol Studies at the University of Nottingham said "This significant year-on-year fall indicates that something in UK tobacco control policy is working, and successful quitting through substitution with e-cigarettes is one likely major contributor." The safety of e-cigarettes has been questioned