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However, this alone cannot explain a 10-fold increase in energy demand, and many other processes may also become very costly in energy

Hepatotoxicity Drug and Toxin-Induced Liver Injury Etiology Hepatotoxicity can be caused by a variety of drugs (prescription or over-the-counter), herbal and dietary supplements, or biologic toxins or chemicals (see Box 61-1).17, 126, 127 The liver is uniquely susceptible to xenobiotic substances because it is directly exposed to them following absorption from the GI tract

Some research suggests that it helps relieve stress under high-stress conditions (such as loss of a loved one, divorce, job loss, etc)