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Hepatocyte-macrophage crosstalk also amplifies alcohol-related inflammation
The modification of drugs and other chemicals that enter the body is carried out by an array of enzymes that mediate reactions that are often termed Phase I or Phase II
Ethics declarations Ethics approval and consent to participate Approved by Ethics Committee, School of Medicine, University of Zagreb, 04-1121-2006 for experiments with rats
1 Introduction Chronic obstructive pulmonary disease (COPD) is a highly prevalent, progressive respiratory disorder characterized by persistent airway inflammation, irreversible airflow limitation, and alveolar destruction ( Emerging evidence now positions ferroptosis not merely as a consequence but as a key amplifier of COPD pathology, particularly through its dynamic interplay with immune dysregulation ( 2 Ferroptosis: a novel form of regulated cell death Ferroptosis is a distinctive type of regulated cell death that significantly differs from apoptosis, necrosis, and autophagy
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