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Significant drug reactions have not been reported. (Rainone, 2005) To answer the question, is milk thistle good for you?, judging by all the benefits it has, including keeping your liver healthy, maintaining your hormonal balance, helping you deal with acne and playing a role in curing your hangovers, the answer is going to have to be a resounding yes

Under conditions of oxidative stress, class I GRXs are assumed to protect reactive thiol groups of proteins from irreversible oxidation by catalysing their glutathionylation and subsequent de-glutathionylation 5,6

Sugano K, Maeda K, Ohtani H, Nagahara H, Shibutani M, Hirakawa K

Glutathione is not one of them