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To reduce the effect of bias, we adjusted observations that did not account for more than five confounders, including age and sex, because they were the significant bias covariates identified by the bias covariate selection algorithm 29 (Supplementary Table 7)

Sans claims coverage up to 1,854 square feet, but with a CADR of 235 cubic feet per minute, (less than the Coway Mighty2 and the Mighty) it would max out at less than 500 square feet at our recommended 4 air changes per hour

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