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Intriguingly, correlation analyses linked microbiota changes to alterations in stress hormones, neurotransmitters, inflammatory markers and anxiety-like behaviors, suggesting a gutbrain contribution to the observed behavioral manifestations in anxiety pathology (Jia et al., 2024

Studies indicate that in mild OA patients, using ferroptosis inhibitors like Ferrostatin-1 (Fer-1) can significantly upregulate GPX4 and SLC7A11 expression while downregulating ACSL4 expression, suggesting the potential for early intervention with these inhibitors (Y

Basilico C, Arnesano A, Galluzzo M, Comoglio PM, Michieli P

doi: 10.1016/j.jss.2015.12.049