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If you notice no stimulating effects, evening dosing is also acceptable

Symptoms of B12 Deficiency Mimic Hypothyroid Symptoms Aside from simply testing for B12 deficiency, you should also be aware of the symptoms associated with this condition

This complex process means that conditions affecting the stomach or intestines can significantly impair B12 absorption, including pernicious anaemia, atrophic gastritis, previous gastric surgery, coeliac disease, Crohn's disease, and long-term use of certain medications (such as metformin, proton pump inhibitors, and H2 antagonists)