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Proc Natl Acad Sci USA 116:1616716169 Galluzzi L, Vitale I, Aaronson SA et al (2018) Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018

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In a 12-week clinical study, obese participants taking 1 mg of AOD-9604 daily lost about 2.62.8 kg (56 lbs) on average more than triple the weight loss of the placebo group