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If the patient is suspected to be sensitive to cobalt or other components of cobalamin, an intradermal test dose is recommended.[12][15] Several laboratory tests should be performed prior to treatment with cyanocobalamin, including serum vitamin B12, folate, iron, hematocrit, and reticulocyte count

This is a sophisticated statistical approach that goes beyond simply averaging results it analyses multiple variables simultaneously and isolates the independent effect of each treatment while controlling for factors that might distort the comparison

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Not approved