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Most individuals in similar situations report meaningful improvement by week 3-4, with some able to reduce cryotherapy frequency while maintaining gains

GSH plays roles in detoxifying toxic compounds, protein folding, the regeneration of vitamins C and E, maintenance of mitochondrial function, antiviral defense, the regulation of cellular proliferation, apoptosis, and the immune response

No significant statistical differences were observed in the basal levels of serum folate, HCY, and B12 among individuals with VCD, those who had recovered from the impairment, and non-impaired individuals, as detailed in Additional file 3