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For inflammatory bowel disease, mesalamine, corticosteroids, immunomodulators (azathioprine, methotrexate), and biologics (infliximab, adalimumab, vedolizumab, ustekinumab) all have Level 1 evidence from Phase III trials with thousands of patients

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GHK-Cu treatment significantly alleviated colitis symptoms, including reduced weight loss, lower disease activity index, and improved colon length and macroscopic damage

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