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Any new or unusual symptoms, including unexplained weight loss beyond expected therapeutic effects, persistent fatigue, or changes in bowel habits, should be reported to your healthcare provider for appropriate evaluation

Long-acting, subcutaneously administered, PYY RA are undergoing early phase clinical trials as obesity treatments either alone or in combination with GLP-1 RA (Table 1, NCT02568306 and NCT03574584)

1 2 "GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism"