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More evidence was provided in the experiments of Cavalleri, L, who found a marked improvement in ketamine-induced synaptic function using dopaminergic (DA) neurons from the mice mesencephalon and human induced pluripotent stem cells, providing visual in vitro evidence for the intervention of ketamine in altering synaptic plasticity [36]

Changes in the expression of muscle-related proteins, such as Atrogin-1, MuRF-1, and Mfn-2, were consistent with the muscle preservation effect of BPC157

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