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To make an APPH case against flavored products, the FDA must show that flavors cause vaping uptake AND that the behavioral response to making flavors unavailable legally would not lead to a more harmful pattern of tobacco and nicotine use, for example, smoking or use of unregulated, criminally supplied ENDS

The journal Health Economics published Understanding the Demand-Side of an Illegal Market: A Case Study of the Prohibition of Menthol Cigarettes in 2025.[11] The authors performed a case study on menthol cigarette bans