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These alternatives may seem less exciting than a cutting-edge peptide injection, but they are grounded in extensive human evidence and carry well-understood risk profiles

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Interestingly, GlyProHyp and ProHyp are the most and second most abundant small 4-hydroxyproline-containing peptides in the plasma of mice, whereas AlaHyp, GlyProHyp and ProHyp are the most, second most, and third most abundant food-derived 4-hydroxyproline-containing peptides in the plasma of adult men and women, at 12 h after the animals and human subjects consumed high amounts of tripeptide (GlyXX)-containing collagen hydrolysates (0.91.8 g/kg BW for mice and 0.3 g/kg BW for humans) (Yazaki et al