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10.1152/japplphysiol.01053.2018 44

doi:10.1111/acel.12368

Research shows increased GLUT4 expression leading to better glucose clearance, enhanced insulin receptor sensitivity, and normalized metabolic parameters

In contrast, iTregs arise in the periphery, where cytokines such as TGF- and IL-2 promote their antigen-induced Foxp3 expression and suppressive function, thereby establishing tolerance to foreign antigens